SpletPleural infection is a common complication of pneumonia and usually requires chest tube drainage. Administration of intrapleural tissue plasminogen activator (tPA) and deoxyribonuclease (DNase) is increasingly used to facilitate pleural fluid evacuation [1, 2]. Splet07. apr. 2024 · The relationship between chest tube size and clinical outcome in pleural infection. Chest 2010; 137:536. Lin CH, Lin WC, Chang JS. Comparison of pigtail catheter with chest tube for drainage of parapneumonic effusion in children. ... Mahant S, Connolly B, et al. Effectiveness of Intrapleural Tissue Plasminogen Activator and Dornase Alfa vs ...
Use of Intrapleural Tissue Plasminogen Activator ... - CHEST
Splet27. nov. 2016 · Like the patients in the above studies (with low drainage (<250mL) in the first 24 hours), he would likely benefit from chest tube placement and intrapleural administration of tPA + dornase alfa. Take … SpletDOI: 10.1148/radiol.2463070235 Abstract Purpose: To retrospectively determine the effectiveness of and risk for hemorrhage with intrapleural adjunctive tissue plasminogen activator (tPA) administered via chest tubes placed with imaging guidance. brad smith blog post
BRONCHOPLEURAL FISTULA COMPLICATION OF INTRAPLEURAL …
Splet01. apr. 2024 · The addition of dornase alfa (DNase) has been reported to improve outcomes in adults but remains unproven in children. Objective: To determine if … SpletThe tPA was inserted into the chest tube while in the contralateral position. The chest tube was then clamped for 1 hour then placed on suction. The most common dose utilized was 25 mg. tPA was instilled daily for three days and then every second or third day based on output. Complete response (80% or greater resolution) occurred in 85% of ... Splet01. feb. 2024 · w Had bilateral chest tube 14 Fr in each side and received 1 dose of coamininstered tPA 10 mg and DNase 5mg in each space. z Complication of intrapleural tPA/DNase: developed self-limited ... brad smoak